منابع مشابه
Risk of osteoporotic fractures after discontinuation of menopausal hormone therapy: results from the E3N cohort.
While current use of menopausal hormone therapy (MHT) reduces the risk of osteoporotic fractures, epidemiologic studies suggest that protection wears off rapidly after discontinuation of treatment. The authors identified 5,589 first osteoporotic fractures (2,235 major osteoporotic fractures) among 70,182 postmenopausal women from the French E3N cohort (1992-2008) and used Cox multivariate propo...
متن کاملChanges in elderly women's health-related quality of life following discontinuation of hormone replacement therapy
BACKGROUND Many women have discontinued hormone replacement therapy (HRT) in view of recent findings. The goal of this study was to determine if HRT discontinuation is associated with changes in health-related quality of life (HRQOL) in elderly women. METHODS We studied women enrolled in Pennsylvania's Pharmaceutical Assistance Contract for the Elderly (PACE) program, linking prescription cla...
متن کاملDiscontinuation of hormone replacement therapy after myocardial infarction and short term risk of adverse cardiovascular events: nationwide cohort study
OBJECTIVE To assess the risk of adverse cardiovascular events in women who discontinue hormone replacement therapy after myocardial infarction compared with those who continue. DESIGN Nationwide register based cohort study. SETTING All hospitals in Denmark. POPULATION All 3322 women aged 40 years or over who survived 30 days after a myocardial infarction and were prescribed hormone replac...
متن کاملAlendronate prevents loss of bone density associated with discontinuation of hormone replacement therapy: a randomized controlled trial.
BACKGROUND Many women using hormone replacement therapy (HRT) will discontinue HRT and lose its bone-protective effect. Methods to preserve bone density in these women need to be explored. This multicenter, international, randomized, blinded, 12-month study was conducted to assess the effect of alendronate sodium on bone density in women who had recently discontinued HRT. METHODS The 144 post...
متن کاملA randomized controlled study of taper-down or abrupt discontinuation of hormone therapy in women treated for vasomotor symptoms.
OBJECTIVE The aim of this study was to investigate whether tapering down of combined estrogen plus progestogen therapy (EPT) reduced the recurrence of hot flashes and resumption of therapy compared with abrupt discontinuation. A secondary aim was to evaluate whether health-related quality of life (HRQoL) was affected after discontinuation of EPT and to investigate the possible factors predictin...
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ژورنال
عنوان ژورنال: Menopause
سال: 2010
ISSN: 1072-3714
DOI: 10.1097/gme.0b013e3181d2ce57